Pure Encapsulations

7-KETO® DHEA, a safe and natural metabolite of DHEA, was the subject of research for over a decade at the University of Wisconsin in Madison. Of over 150 DHEA compounds tested, 7-Keto® proved to be the most promising form. Researchers discovered that 7-Keto® does not convert to testosterone or estrogen, minimizing androgenic activity, and supports various physiological processes. It is several times more potent than DHEA in stimulating the thermogenic enzymes of the liver, promotes basal metabolism, and helps to increase the lean/adipose ratio. These actions safely support a leaner BMI (Body Mass Index) and healthy weight control as part of a healthy lifestyle with a reduced calorie diet and regular exercise. In a double-blind study involving 30 overweight adults, 7-Keto® supported healthy body composition and BMI when combined with exercise. 7-KETO® DHEA is also known as DHEA-Acetate-7-one, 3-acetoxy-androst-5-ene-7, 17-dione, or 3-acetyl-7-oxodehydroepiandrosterone.*

Alpha lipoic acid is both water and fat-soluble which allows it to function in almost any part of the body as an antioxidant. A key component of the metabolic process, alpha lipoic acid produces energy in muscles and directs calories into energy production. Also, it helps maintain healthy glucose metabolism, supports the nervous system and provides nutritional support for healthy liver function. Alpha lipoic acid supported nerve health in subjects who participated in a randomized, double-blind, placebo-controlled, multicenter trial. The ability of alpha lipoic acid to modulate nitric oxide metabolite activity and to promote healthy microcirculation accounted for its ability to promote nerve cell health in two separate studies.* Alpha Lipoic Acid is a multifunctional nutrient which plays a key role in the antioxidant network and the metabolic process.*

Ascorbic Acid (the purest form of vitamin C) offers a wide range of support for the human body. It is a potent antioxidant and free radical scavenger. It supports the body's defense system by enhancing white blood cell function and activity, and increasing interferon levels, antibody responses, and secretion of thymic hormones. It is essential for the formation and maintenance of intercellular ground substance and collagen. Vitamin C aids in the absorption of iron and the formation of red blood cells and converts folic acid to active folinic acid. It maintains healthy histamine release and supports lymphocyte formation. Vitamin C is also required for the synthesis of carnitine and steroids.* Vitamin C, one of the most potent dietary antioxidants, provides optimal nutritional support to all physiological functions, including, notably, vascular and capillary integrity in support of the circulatory system.*

Ascorbic Acid (the purest form of vitamin C) offers a wide range of support for the human body. It is a potent antioxidant and free radical scavenger. It supports the body's defense system by enhancing white blood cell function and activity, and increasing interferon levels, antibody responses, and secretion of thymic hormones. It is essential for the formation and maintenance of intercellular ground substance and collagen. Vitamin C aids in the absorption of iron and the formation of red blood cells and converts folic acid to active folinic acid. It maintains healthy histamine release and supports lymphocyte formation. Vitamin C is also required for the synthesis of carnitine and steroids.* Vitamin C, one of the most potent dietary antioxidants, provides optimal nutritional support to all physiological functions, including, notably, vascular and capillary integrity in support of the circulatory system.*

Ascorbic Acid (the purest form of vitamin C) offers a wide range of support for the human body. It is a potent antioxidant and free radical scavenger. It supports the body's defense system by enhancing white blood cell function and activity, and increasing interferon levels, antibody responses, and secretion of thymic hormones. It is essential for the formation and maintenance of intercellular ground substance and collagen. Vitamin C aids in the absorption of iron and the formation of red blood cells and converts folic acid to active folinic acid. It maintains healthy histamine release and supports lymphocyte formation. Vitamin C is also required for the synthesis of carnitine and steroids.* Vitamin C, one of the most potent dietary antioxidants, provides optimal nutritional support to all physiological functions, including, notably, vascular and capillary integrity in support of the circulatory system.*

Ashwagandha, Withania somnifera, is an adaptogenic herb that belongs to the pepper family. It has an extensive, 4,000-year history of traditional use and is one of the most revered and widely used Ayurvedic herbs. Withanolides are key constituents of this herb and play an important role in ashwagandha’s overall ability to promote physical and mental health. In animal studies, ashwagandha has been shown to support the activity of lymphocytes and macrophages, moderate occasional stress, support memory and cognitive function, provide neurosupport by scavenging free radicals, and support thyroid function. A small human clinical trial demonstrated the ability of ashwagandha to support healthy glucose and lipid metabolism.*

Derived from Haematococcus Pluvialis microalgae cultivated under pristine conditions, esterified astaxanthin is a stable, fat-soluble antioxidant from the carotenoid family. Astaxanthin protects the phospholipid membranes of cells from oxidative damage. In a recent U.S. study, it demonstrated the ability to cross the blood-brain barrier and protect the retina in animals, suggesting its potential for supporting the brain and nervous system from free radical damage. Initial trials with astaxanthin suggest that it may support the skin’s natural antioxidant defenses. In a human clinical evaluation, supplementation with astaxanthin provided enhanced antioxidant protection for the skin. Additional studies suggest astaxanthin’s immune, cellular and cardiovascular support potential.*

Vitamin/Mineral Distinctions: Potassium phosphate combined with calcium and magnesium for healthy muscle function, and copper, manganese, selenium, and zinc for healthy tendons, ligaments, and joints* Supports stamina and buffers lactic acid with highly pure creatine monohydrate; research indicates the potential to increase optimal work output in activities such as weight-lifting and sprinting. Contains other ATP cofactors, including CoQ10 and alpha ketoglutarate.*

Broad-spectrum B vitamin support. This balanced combination of functionally interrelated B vitamins provides wide-ranging benefits, including methylation, nerve, and energy support. • Comprehensive B vitamin supplement • Includes researched and activated forms, including pyridoxal-5-phosphate, riboflavin-5-phosphate, and folate as 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate* • Made with hypoallergenic, vegan ingredients

Comprehensive B vitamin supplement with enhanced levels of vitamin B6 to support proper functioning of the nervous system and healthy cognitive function. Includes researched and activated forms, including pyridoxal-5-phosphate, riboflavin-5-phosphate, and folate as 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate. Enhanced with vitamin B6 to promote healthy neurological function. Offers vitamin B12 in a unique blend of adenosylcobalamin and hydroxycobalamin. Includes choline and inositol to support healthy methylation and cognitive function.*

5,000 mcg per 1 ml serving; Recent research has indicated that methylcobalamin, the active form of vitamin B12, supports neurological function and nerve cell health. In studies, methylcobalamin has demonstrated the potential to support healthy cognitive and nerve function as well as memory and emotional well–being. Vitamin B12 is also an important cofactor for energy production and plays a role in immune system health and healthy homocysteine metabolism.* • Support for nerve health and cognitive function* • Promotes overall emotional well-being* • Made with hypoallergenic, vegetarian ingredients • Convenient, great-tasting liquid formula for easy dispensing

This blend provides support for occasional sleeplessness. It contains the time-tested support of valerian, passionflower, chamomile, lemon balm, and hops; which act to calm and relax the central nervous system. Double-blind trials involving valerian, valerian/lemon balm combinations and valerian/hops combinations have indicated the potential to support the onset of sleep as well as healthy sleep quality. Melatonin also facilitates the onset of sleep and sleep efficiency. GABA and l-theanine are included for their ability to promote alpha wave production in the brain, an indication of relaxation.*

Betaine HCl and pepsin are gastric-juice components essential to the digestion of food and absorption of most nutrients. In particular, betaine HCl is necessary for adequate absorption of protein, calcium, vitamin B12, and iron. The low pH of the stomach’s hydrochloric acid destroys ingested bacteria and microorganisms. This formula can be beneficial for anyone seeking enhanced support for digestive function.*

Biotin is a water-soluble B vitamin that is an essential co-factor for several carboxylation reactions involved in metabolism. Recent studies have expanded biotin’s metabolic role, claiming that the vitamin maintains healthy genetic expression of the many enzymes for which it is a cofactor*

Bromelain is a proteolytic enzyme from the stem of the pineapple plant. Taken with food, bromelain aids in the proper functioning of the digestive system. Taken between meals, bromelain inhibits the production of kinins and fibrin, which promote the inflammatory process.

Buffered ascorbic acid combines calcium ascorbate, magnesium ascorbate, and potassium ascorbate to create a neutral pH vitamin C. This special form of ascorbic acid lessens possible gastric irritation in sensitive individuals. • Vitamin C for sensitive individuals • Buffered ascorbic acid combines calcium ascorbate, magnesium ascorbate, and potassium ascorbate to create a neutral pH vitamin C.* • This special form of ascorbic acid lessens possible gastric irritation in sensitive individuals.*

Buffered ascorbic acid combines calcium ascorbate, magnesium ascorbate, and potassium ascorbate to create a neutral pH vitamin C. This special form of ascorbic acid lessens possible gastric irritation in sensitive individuals. • Vitamin C for sensitive individuals • Buffered ascorbic acid combines calcium ascorbate, magnesium ascorbate, and potassium ascorbate to create a neutral pH vitamin C.* • This special form of ascorbic acid lessens possible gastric irritation in sensitive individuals.*

The buffered ascorbic acid powder combines calcium ascorbate, magnesium ascorbate, and potassium ascorbate to create a neutral pH vitamin C. This special form of ascorbic acid lessens possible gastric irritation in sensitive individuals. • Vitamin C for sensitive individuals • Buffered ascorbic acid combines calcium ascorbate, magnesium ascorbate, and potassium ascorbate to create a neutral pH vitamin C.* • This special form of ascorbic acid lessens possible gastric irritation in sensitive individuals.*"

Highly absorbable and researched calcium chelate; supports colon health*. Numerous studies have reported that statistically significant benefits of calcium supplementation may help reduce the risk of osteoporosis for both women and men when providing adequate calcium throughout life as part of a well-balanced diet.* Research also suggests that calcium is associated with supporting distal colon health.* • Calcium for bone and cardiovascular support* • Made with hypoallergenic, vegan ingredients

Caprylic acid, also known as octanoic acid, is a naturally occurring fatty acid that promotes a favorable environment for beneficial microflora. Due to its fat solubility, it is believed to penetrate intestinal mucosal cells to exert its effects.* • Gradual release, buffered caprylic acid* • Made with hypoallergenic, vegan ingredients

Chaste tree extract, also known as Vitex, contains flavonoids, iridoid glycosides, and terpenoids. It has been associated with supporting breast comfort and positive mood during the menstrual cycle, as suggested by numerous randomized, double-blind, placebo-controlled trials. It has also been associated with promoting healthy menstrual luteal phase length and menstrual regularity for some women, helping to maintain healthy reproductive system function.*

ChromeMate® has been clinically studied for its potential role in supporting healthy body composition when combined with a healthy diet and exercise. One study showed that when combined with modest diet and exercise, ChromeMate® supported lean body composition in overweight women. A similar study also suggested that ChromeMate® may support lean muscle mass in overweight women. The potential for ChromeMate® to promote Glucose Tolerance Factor (GTF) activity accounts for its role in maintaining healthy glucose metabolism and supporting body composition* • Made with hypoallergenic, vegan ingredients

ChromeMate® has been clinically studied for its potential role in supporting healthy body composition when combined with a healthy diet and exercise. One study showed that when combined with modest diet and exercise, ChromeMate® supported lean body composition in overweight women. A similar study also suggested that ChromeMate® may support lean muscle mass in overweight women. The potential for ChromeMate® to promote Glucose Tolerance Factor (GTF) activity accounts for its role in maintaining healthy glucose metabolism and supporting body composition* • Made with hypoallergenic, vegan ingredients

Copper activates several of enzymes important to energy metabolism. It is the key mineral in lysyl oxidase, an enzyme which weaves together collagen and elastin. Copper assists in the formation of hemoglobin and red blood cells by facilitating iron absorption. It is involved in protein metabolism, the production of RNA, and the synthesis of phospholipids used in the formation of myelin sheaths.*

Cranberry concentrate provides urinary tract support without the unwanted sugar found in cranberry juice or juice cocktails. It enhances the acidity of urine and maintains a healthy urinary tract ecology. A randomized double-blind, placebo-controlled trial involving over 150 female volunteers reported positive support for a healthy urinary tract after administration of a cranberry beverage. d-Mannose, a simple sugar found in cranberries and other fruit, is included in this formula to provide enhanced support. One study suggested that d-Mannose may play a role in supporting healthy genitourinary function by maintaining a healthy mucosal surface.* • Dual support for urinary tract comfort* • Promotes urinary tract functionality* • Made with cranberry extract from 100% cranberry fruit solids* • Made with hypoallergenic, vegan ingredients

Cranberry concentrate provides urinary tract support without the unwanted sugar found in cranberry juice or juice cocktails. It enhances the acidity of urine and maintains a healthy urinary tract ecology. A randomized double-blind, placebo-controlled trial involving over 150 female volunteers reported positive support for a healthy urinary tract after administration of a cranberry beverage. d-Mannose, a simple sugar found in cranberries and other fruit, is included in this formula to provide enhanced support. One study suggested that d-Mannose may play a role in supporting healthy genitourinary function by maintaining a healthy mucosal surface.* • Dual support for urinary tract comfort* • Promotes urinary tract functionality* • Made with cranberry extract from 100% cranberry fruit solids* • Made with hypoallergenic, vegan ingredients

CurcumaSorb provides the patented Meriva® curcumin-phosphatidylcholine complex for enhanced-absorption and bioavailability. The proprietary phytosome technology combines curcumin and phosphatidylcholine at a 1:2 ratio, promoting resistance to degradation in the digestive tract and efficient absorption across membranes. This produces significantly higher peak plasma concentrations and larger area under concentration-time curves (AUC). In a single-dose pharmacokinetic animal study, plasma curcumin levels were 20-fold greater with Meriva® than standard curcumin. A preliminary human pharmacokinetic study demonstrated that elevations in plasma curcumin from 450 mg Meriva® were similar to values obtained from 4,000 mg of a standard curcumin extract. The efficacy of a low dose was demonstrated in a three-month clinical trial, in which 200 mg curcuminoids from Meriva® per day provided significant benefit in joint comfort, mobility and quality of life.*

Curcumin has a long history of use for supporting healthy cyclooxygenase, prostaglandin and leukotriene metabolism. It also appears to provide important antioxidant defense. Furthermore, it supports the body’s natural detoxification system and helps maintain healthy hepatic function. These actions are associated with its beneficial effects, including support for healthy liver, colon, musculoskeletal, and cellular function. Curcumin C3 Complex® has been the subject of scientific investigations at several hospitals, and universities. Most recently, it has demonstrated the potential to maintain healthy tissue in the brain by supporting macrophage activity and has been associated with support for cellular health in separate trials. Bioperine® is a black pepper extract that contains the alkaloid piperine. Research reveals that it has the potential to enhance the bioavailability of curcumin, promoting its absorption.*

Curcumin has a long history of use for supporting healthy cyclooxygenase, prostaglandin and leukotriene metabolism. It also appears to provide important antioxidant defense. Furthermore, it supports the body’s natural detoxification system and helps maintain healthy hepatic function. These actions are associated with its beneficial effects, including support for healthy liver, colon, musculoskeletal, and cellular function. Curcumin C3 Complex® has been the subject of scientific investigations at several hospitals, and universities. Most recently, it has demonstrated the potential to maintain healthy tissue in the brain by supporting macrophage activity and has been associated with support for cellular health in separate trials. Bioperine® is a black pepper extract that contains the alkaloid piperine. Research reveals that it has the potential to enhance the bioavailability of curcumin, promoting its absorption.*

This combination of deglycyrrhizinated licorice (DGL) and herbal extracts provides nutritional support to the gastrointestinal tract. DGL Plus® supports the body's natural defense mechanisms by stimulating the mass, quality, and production of mucous, a major component of the stomach's protective lining. DGL is free of side effects typically associated with licorice.*

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. It is chemically similar to testosterone and estrogen, and is easily converted into those hormones. DHEA production peaks in early adulthood, and declines with age. Thus, many health concerns which correlate with age may also correlate with low levels of DHEA production. DHEA levels are often found to be low in instances of adrenal insufficiency. DHEA supplies 5 mg of DHEA, and is also available in 10 mg & 25mg doses. Made with hypoallergenic, vegan ingredients

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. It is chemically similar to testosterone and estrogen, and is easily converted into those hormones. DHEA production peaks in early adulthood, and declines with age. Thus, many health concerns which correlate with age may also correlate with low levels of DHEA production. DHEA levels are often found to be low in instances of adrenal insufficiency. DHEA supplies 5 mg of DHEA, and is also available in 10 mg & 25mg doses. Made with hypoallergenic, vegan ingredients

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. It is chemically similar to testosterone and estrogen, and is easily converted into those hormones. DHEA production peaks in early adulthood, and declines with age. Thus, many health concerns which correlate with age may also correlate with low levels of DHEA production. DHEA levels are often found to be low in instances of adrenal insufficiency. DHEA supplies 10mg of DHEA, and is also available in 25mg & 5mg doses. Made with hypoallergenic, vegan ingredients

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. It is chemically similar to testosterone and estrogen, and is easily converted into those hormones. DHEA production peaks in early adulthood, and declines with age. Thus, many health concerns which correlate with age may also correlate with low levels of DHEA production. DHEA levels are often found to be low in instances of adrenal insufficiency. DHEA supplies 10mg of DHEA, and is also available in 25mg & 5mg doses. Made with hypoallergenic, vegan ingredients

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. It is chemically similar to testosterone and estrogen, and is easily converted into those hormones. DHEA production peaks in early adulthood, and declines with age. Thus, many health concerns which correlate with age may also correlate with low levels of DHEA production. DHEA levels are often found to be low in instances of adrenal insufficiency. DHEA supplies 25 mg of DHEA, and is also available in 10 mg & 5mg doses. Made with hypoallergenic, vegan ingredients

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. It is chemically similar to testosterone and estrogen, and is easily converted into those hormones. DHEA production peaks in early adulthood, and declines with age. Thus, many health concerns which correlate with age may also correlate with low levels of DHEA production. DHEA levels are often found to be low in instances of adrenal insufficiency. DHEA supplies 25 mg of DHEA, and is also available in 10 mg & 5mg doses. Made with hypoallergenic, vegan ingredients

Digestive Enzymes Ultra contains an extensive profile of vegetarian digestive enzymes. Proteases included in this formula provide optimal activity across a wide pH range. They facilitate the normal breakdown of proteins and di- and tri-peptides. Lipase promotes lipid breakdown, while amylase and glucoamylase are included to stimulate polysaccharide breakdown of starch and glycogen. Invertase and lactase support the digestion of carbohydrate disaccharides, including the dairy sugar lactose. This formula also offers numerous enzymes to support fiber breakdown, including cellulase, hemicellulase, beta-glucanase, and phytase. These enzymes act to break down cell wall components and phytic acid, promoting nutrient bioavailability of fiber-containing foods. Additionally, alphagalactosidase promotes the breakdown of certain complex carbohydrates, such as raffinose and stachyose, found in some vegetables, grains, and legumes— helping to relieve occasional bloating or gas.* • Made with hypoallergenic, vegetarian ingredients

Digestive Enzymes Ultra contains an extensive profile of vegetarian digestive enzymes. Proteases included in this formula provide optimal activity across a wide pH range. They facilitate the normal breakdown of proteins and di- and tri-peptides. Lipase promotes lipid breakdown, while amylase and glucoamylase are included to stimulate polysaccharide breakdown of starch and glycogen. Invertase and lactase support the digestion of carbohydrate disaccharides, including the dairy sugar lactose. This formula also offers numerous enzymes to support fiber breakdown, including cellulase, hemicellulase, beta-glucanase, and phytase. These enzymes act to break down cell wall components and phytic acid, promoting nutrient bioavailability of fiber-containing foods. Additionally, alphagalactosidase promotes the breakdown of certain complex carbohydrates, such as raffinose and stachyose, found in some vegetables, grains, and legumes— helping to relieve occasional bloating or gas.* • Made with hypoallergenic, vegetarian ingredients

Offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range. Supports optimal gastric pH with betaine HCl, important for the enhanced digestion of protein and other nutrients to support daily wellness and neurotransmitter synthesis. Facilitates the normal breakdown of proteins, peptides, fats, polysaccharides and disaccharides.*

Digestion GB contains gallbladder digestive enzymes, bile salts, taurine, and herbal extracts to promote healthy gall bladder function and fat utilization. The metabolism of fats involves emulsification and digestion in a complex process that requires healthy liver, gallbladder and pancreas function. Milk thistle, curcumin, and taurine promote liver and gallbladder health and stimulate production and secretion of bile acids. Bile acids, also provided in the form of ox bile salts, support the emulsification of fats necessary for digestion. The digestive enzymes included in this formula are active in a broad pH range to support fat, carbohydrate and protein digestion to complement pancreatic enzyme activity. This formula has enhanced lipase for extra fat digestion support.* • Digestive enzyme formula* • Made with hypoallergenic ingredients

Digestion GB contains gallbladder digestive enzymes, bile salts, taurine, and herbal extracts to promote healthy gall bladder function and fat utilization. The metabolism of fats involves emulsification and digestion in a complex process that requires healthy liver, gallbladder and pancreas function. Milk thistle, curcumin, and taurine promote liver and gallbladder health and stimulate production and secretion of bile acids. Bile acids, also provided in the form of ox bile salts, support the emulsification of fats necessary for digestion. The digestive enzymes included in this formula are active in a broad pH range to support fat, carbohydrate and protein digestion to complement pancreatic enzyme activity. This formula has enhanced lipase for extra fat digestion support.* • Digestive enzyme formula* • Made with hypoallergenic ingredients

The glucosinolates in broccoli, including indole-3-carbinol and sulforaphane, help support healthy detoxification. BioResponse DIM® provides 25 mg per serving of a highly absorbable form of diindolylmethane, an important metabolite of indole-3-carbinol. These compounds promote healthy estrogen metabolism and cell cycle activity. Calcium-D-glucarate targets betaglucuronidase enzyme activity, promoting healthy hormone detoxification through the glucuronidation pathway. Lignans, such as 7-hydroxymatairesinol (HMR), are converted in the body to enterolactone. Research indicates that dietary intake of lignans and healthy serum enterolactone levels provide support for cellular, heart, breast, bone and cognitive health. Silymarin, alpha lipoic acid and n-acetyl-l-cysteine act to support phase II detoxification enzyme activity in the liver and offer antioxidant support for cellular protection. Taurine, glycine, and methionine promote phase II detoxification pathways and healthy cell metabolism.*

DIM-PRO® 100 contains BioResponse DIM® (diindolylmethane complex). Diindolylmethane is a metabolite of indole-3-carbinol (I3C). Both are found naturally in cruciferous vegetables like broccoli, kale and brussels sprouts. Upon contact with gastric acid in the stomach, I3C is converted to a number of active compounds, predominantly diindolylmethane. Research indicates that diindolylmethane supports healthy cell cycle function and signal transduction to maintain breast, cervical and prostate cell health. In a double-blind, randomized clinical trial, BioResponse DIM® revealed potential support for maintaining the function of healthy breast cells. Another randomized placebo-controlled crossover trial found that it promoted statistically significant breast comfort. Furthermore, an additional double-blind randomized clinical trial with 52 women found that BioResponse DIM® supported cervical cell health. Diindolylmethane in its pure form is highly insoluble. Patented, microencapsulated BioResponse DIM® has been specially developed for enhanced-absorption. This form may be more supportive than I3C in cases of low gastric acidity.* • Made with vegan ingredients

DIM-PRO® 100 contains BioResponse DIM® (diindolylmethane complex). Diindolylmethane is a metabolite of indole-3-carbinol (I3C). Both are found naturally in cruciferous vegetables like broccoli, kale and brussels sprouts. Upon contact with gastric acid in the stomach, I3C is converted to a number of active compounds, predominantly diindolylmethane. Research indicates that diindolylmethane supports healthy cell cycle function and signal transduction to maintain breast, cervical and prostate cell health. In a double-blind, randomized clinical trial, BioResponse DIM® revealed potential support for maintaining the function of healthy breast cells. Another randomized placebo-controlled crossover trial found that it promoted statistically significant breast comfort. Furthermore, an additional double-blind randomized clinical trial with 52 women found that BioResponse DIM® supported cervical cell health. Diindolylmethane in its pure form is highly insoluble. Patented, microencapsulated BioResponse DIM® has been specially developed for enhanced-absorption. This form may be more supportive than I3C in cases of low gastric acidity.* • Made with vegan ingredients

DL-Phenylalanine is a combination of the well-tolerated essential amino acids, d-phenylalanine and l-phenylalanine. Together, these compounds help promote mental functioning and support positive outlook. l-Phenylalanine is a precursor to l-tyrosine, which converts to the neurotransmitters norepinephrine, epinephrine, dopamine and tyramine. l-Tyrosine and its metabolites may support emotional well-being, memory and learning. d-Phenylalanine may promote the levels of certain endorphins, thereby calming stressed muscles and joints.* • Made with hypoallergenic, vegan ingredients By maintaining healthy tyrosine and endorphin levels, dl-phenylalanine nutritionally supports mental acuity and emotional well-being, while relaxing stressed muscles and joints.

D-Mannose is a simple sugar found naturally in cranberries and pineapples. It is metabolized in small amounts, the remainder of which is excreted via the urine. As it is flushed out of the body, D-mannose maintains a healthy environment for the mucosal surface of the urinary tract.* • Supports healthy urinary function* • Ingredients are naturally found in cranberries and pineapples* • Convenient powder formula for easy dispensing • Made with hypoallergenic, vegan ingredients

• Provides the dopamine precursors l-tyrosine and L-DOPA from Mucuna pruriens* • In a randomized, controlled, double-blind, crossover trial, Mucuna pruriens supplementation promoted L-DOPA plasma concentrations* • Includes the cofactors vitamin B6, Metafolin® L-5-MTHF, and zinc to support dopamine production* • Promotes the stability of dopamine and maintains healthy dopamine reuptake with rhodiola and green tea polyphenols* • Supports cognitive function and mental sharpness with grape seed proanthocyanidins* • Protects neuronal health and function with green tea and grape seed polyphenols* • Supports optimal serum levels of zinc and folate to promote positive mood* • Supports dopamine production* • Promotes mental function and sharpness* • Made with hypoallergenic, vegan ingredients

Combines an ultra-pure, molecularly distilled triglyceride fish oil with cold-pressed borage oil to support joint, skin and eye health* Extensive clinical research has indicated that essential fatty acids support the health of joints, skin and eyes. EPA, DHA and GLA support joint, skin and eye health through a broad range of mechanisms involving cytokine balance, protease activity, immune mediator activity and blood flow. The importance of GLA has been underscored by clinical studies with favorable musculoskeletal and dermatologic outcomes. While omega-3 fatty acids are utilized for the biosynthesis of prostaglandin E3, the omega-6 fatty acid, GLA, is an important precursor of prostaglandin E1. Together, EPA, DHA and GLA help to balance eicosanoid production in diverse cell types, including chondrocytes in joints, keratinocytes of the skin, and epithelial cells of the eye. EPA, DHA and GLA support joint health by maintaining healthy cytokine activity and matrix protease expression. GLA also supports skin elasticity and hydration through promoting peripheral blood flow and nutrient delivery. Clinical research has indicated important roles of fish oil and GLA-rich oils in maintaining moisture retention in the epithelia of the eyes. Large studies have indicated that EPA and DHA support ocular hydration through promoting healthy tear production and tear film osmolarityin normally functioning eyes. GLA provides additional support for ocular health by maintaining mucin production and healthy tear film characteristics.*

Supports hydration, stamina, and electrolyte repletion*, , • Combines sodium, chloride, potassium, calcium, and magnesium to replenish electrolytes lost during exercise; supports muscle function, retains hydration, may lessen the perception of exertion*, • Provides glucose and maltodextrin, important pre-exercise sources of rapidly available energy; spares glycogen stores and delays fatigue*, • Contains the energizing cofactors malic acid and alpha ketoglutarate, both Krebs cycle intermediates*, • Includes vitamin C to protect muscles from free radicals generated during exercise and to support tissue recovery*, • Supports mental focus under stressful conditions and may also help promote physical endurance with the amino acid l-tyrosine, a neurotransmitter precursor*, • Especially for strenuous or prolonged exercise at least 1-2 hours in length, • Helps replenish electrolytes that are lost during exercise*, • Supports physical and mental stamina*, • Includes vitamin C to enhance tissue recovery*, • Includes vitamin C to support tissue recovery*, • Made with hypoallergenic, vegan ingredients

Ester-C®, consisting primarily of calcium ascorbate, is a natural, non-acidic water-soluble form of vitamin C that is distinguished by its unique chemical composition and biological activity. It is manufactured in an exclusive, water-based process that results in a mixture of naturally occurring vitamin C metabolites, including ascorbate, dehydroascorbate, and threonate. The bioflavonoids quercetin, rutin, and pomegranate extract are free radical scavengers that complement the roles of vitamin C. Quercetin helps maintain healthy mast cell function, moderates healthy leukotriene and prostaglandin metabolism. Rutin and pomegranate extract provide important support for blood vessel integrity and healthy cell function.*

GABA is the primary inhibitory neurotransmitter in the central nervous system, playing a central role in regulating cell-to-cell communication. Healthy levels have been associated with a positive mood. A recent study indicates that GABA also supports alpha wave production in the brain to promote relaxation and moderate occasional stress. In the same study, it supported healthy IgA levels, suggesting that it may support immune health during occasional stress.* • Helps moderate occasional stress* • Regulates cell-to-cell communication* • Made with hypoallergenic, vegan ingredients

GABA is the primary inhibitory neurotransmitter in the central nervous system, playing a central role in regulating cell-to-cell communication. Healthy levels have been associated with a positive mood. A recent study indicates that GABA also supports alpha wave production in the brain to promote relaxation and moderate occasional stress. In the same study, it supported healthy IgA levels, suggesting that it may support immune health during occasional stress.* • Helps moderate occasional stress* • Regulates cell-to-cell communication* • Made with hypoallergenic, vegan ingredients

This item has been discontinued by the manufacturer

Glycine is the simplest amino acid; its side chain consists of just a single hydrogen atom. Supplementation with glycine has been shown to support healthy kidney and liver function as well as nervous system health. Animal studies and a small human study indicate that glycine has the potential to support memory and mental function. In another human trial, glycine, acting as an inhibitory amino acid, had neuroprotective effects. Animal studies suggest that glycine plays a protective role for the kidneys and liver particularly by supporting detoxification of certain chemicals.*

The grapefruit seed extract is a highly concentrated G.I. balancing extract promoting healthy microflora and gut ecology. A preliminary clinical trial reported that grapefruit seed extract supplements helped support healthy G.I. function and comfort. An in vitro study indicated that grapefruit seed extract promoted healthy microbial balance. Other studies support these findings, citing that grapefruit seed extract promotes a healthy environment when exposed to a wide range of bacterial biotypes.*

Hawthorn extract provides nutritional support for healthy cardiovascular function. This herbal formula supports coronary flow, healthy heart tissue, and myocardial function.*

Inositol is a component of the B-complex family. It plays an important role in cell membrane formation and supports the serotonin, norepinephrine and cholinergic receptor functions. As a result, inositol may support healthy mood, emotional wellness/behavior, and help lessen occasional nervous tension.

l-Arginine supports nitric oxide formation, important for healthy dilation of blood vessels, circulation, and blood flow. In trials, l-arginine has demonstrated the potential to support endothelial function in blood vessels, platelet function, exercise tolerance, and sexual function.* Because of its effect on nitric oxide production, l-arginine is theoretically best avoided by individuals with migraines, depression, autoimmune disorders, and kidney or liver disease. l-Arginine is contraindicated for individuals with the herpes virus.

l-Carnitine is an amino acid found abundantly in skeletal and heart muscle. It functions primarily to support fat utilization. Also acts as a carrier of fatty acids into the mitochondria, where they are oxidized and converted to energy. l-Carnitine also facilitates the removal of short and medium-chain fatty acids from the mitochondria that accumulate during normal metabolic processes. A randomized double-blind, placebo-controlled trial of l-carnitine involving 101 volunteers indicated that l-carnitine helped maintain healthy cardiac enzymes including lipid peroxides and lactate dehydrogenase. In combination with other cardiovascular support agents, l-carnitine supported ventricular function and superoxide dismutase enzyme activity in human volunteers. Long-term l-carnitine supplementation indicated positive support for cardiovascular health after a 3-year follow-up in adult subjects. A recent placebo-controlled clinical study found that l-carnitine-l-tartrate supplementation helps physical recovery from high- intensity exercise. l-Carnitine-l-tartrate contains 68% pure l-carnitine and 32% natural l-tartaric acid.*

l-Carnosine (beta-alanyl-L-histidine) occurs naturally in the body’s muscle and nervous tissues and is formed by the amino acids alanine and histidine. Levels of this dipeptide can decline with age. It is a water-soluble antioxidant and promotes cell health and cell longevity. In vitro, l-carnosine maintains healthy advanced glycation end-product, or AGE, activity. These end-products are formed when aldehydes (such as aldose and ketose sugars) and lipid peroxidation by-products bind to proteins. l-Carnosine plays a role in maintaining DNA integrity. l-Carnosine may also support superoxide dismutase activity. In addition, l-carnosine may help to maintain healthy peptide metabolism in the brain and its membrane-stabilizing properties support cellular health in the cardiovascular system. The concentration of l-carnosine in the muscle may prove to be an important factor in high-intensity exercise performance based on a recent human study.*

Glutathione is found in virtually every cell of the body and plays a critical role in protein synthesis, enzyme function, transport, and cell maturation. Offers the key antioxidant glutathione in a liposomal form, which protects glutathione bonds from the degradation that can occur in digestion. Protects the body from free radicals to support cellular function and homeostasis. Offers antioxidant support for liver tissue protection; the highest concentration of glutathione is found in the liver. Maintains healthy lipid metabolism and oxidative status.*

l-Lysine, an amino acid, provides nutritional support for the body's natural defenses. l-Lysine is particularly helpful in maintaining healthy gum and lip tissue.*

l-Lysine, an amino acid, provides nutritional support for the body's natural defenses. l-Lysine is particularly helpful in maintaining healthy gum and lip tissue.*

The essential amino acid l-tryptophan is a serotonin precursor. Research indicates that l-tryptophan supplementation may support emotional well-being and restful sleep. In a double-blind, placebo-controlled study, l-tryptophan supported healthy emotional processing and promoted positive outlook in women. In a separate study, it supported healthy mood and lessened occasional irritability during the menstrual cycle. l-Tryptophan also supports healthy sleep quality, onset and duration. Additional research suggests that tryptophan may promote relaxation and help control occasional cravings. Vitamin B6 provides enhanced support as important cofactors involved in the metabolism of l-tryptophan.*

l-Tyrosine supports production of various neurotransmitters that support emotional well-being and cognitive function. I-Tyrosine plays an important role in promoting healthy neurotransmitter function in response to mild environmental and emotional stress.*

Lutein is a carotenoid found in a vast number of fruits and vegetables. Pure Encapsulations' free-form Lutein is structurally identical to the lutein found naturally in spinach and other leafy greens. Like other carotenoids, lutein has antioxidant activity in various tissues but is one of only two that are stored within the retina, where lutein promotes the integrity and density of the macular pigment, a key component of ocular health. Multiple clinical studies suggest a direct relationship between lutein supplementation and macula lutein concentration. Lutein uptake reportedly occurs in the receptor layer of the eye through a soluble carotenoid-binding protein called tubulin. Clinical trials have indicated that lutein specifically supports vision health through a combination of pigment associated antioxidant protection and light screening mechanisms. Furthermore, a two-year, double-blind, placebo-controlled pilot study reported that lutein may support healthy visual function in older individuals more efficiently than alpha-tocopherol.* • Made with hypoallergenic ingredients

LVR Formula helps support liver function with antioxidants designed to offer multifaceted liver cell protection. The flavonoid components in silymarin, curcumin, and artichoke have free radical scavenging activities, helping to protect and promote liver cell health. Studies indicate that silymarin supports healthy liver metabolism, hepatocyte protein synthesis, and DNA integrity within the liver cells. Curcumin offers additional cellular protection support. Luteolin is a key component found in artichoke. Research suggests that it promotes healthy matrix metalloproteinase activity to support healthy liver tissue. N-Acetyl-l-cysteine (NAC) is a precursor of the endogenous antioxidant glutathione. In the body, NAC supports healthy detoxification processes. Experimental models suggest that the antioxidant properties of alpha lipoic acid provide further liver cell protection.* • Antioxidant support for liver cell health* • Made from artichoke extract and other plant-based ingredients • Made with hypoallergenic ingredients

LVR Formula helps support liver function with antioxidants designed to offer multifaceted liver cell protection. The flavonoid components in silymarin, curcumin, and artichoke have free radical scavenging activities, helping to protect and promote liver cell health. Studies indicate that silymarin supports healthy liver metabolism, hepatocyte protein synthesis, and DNA integrity within the liver cells. Curcumin offers additional cellular protection support. Luteolin is a key component found in artichoke. Research suggests that it promotes healthy matrix metalloproteinase activity to support healthy liver tissue. N-Acetyl-l-cysteine (NAC) is a precursor of the endogenous antioxidant glutathione. In the body, NAC supports healthy detoxification processes. Experimental models suggest that the antioxidant properties of alpha lipoic acid provide further liver cell protection.* • Antioxidant support for liver cell health* • Made from artichoke extract and other plant-based ingredients • Made with hypoallergenic ingredients

Lutein and zeaxanthin are the two major carotenoid pigments stored in the macula, the central part of the retina. They are believed to promote the integrity and density of the macular pigment through antioxidant properties. In addition, they help form a protective layer that filters light, maintaining a healthy photoreceptor function in the macula. Increased intake of these carotenoids is associated with increased macular concentration. Numerous double-blind, placebo-controlled trials indicate that lutein and zeaxanthin support the health of the optical lens as well as the retina. Additionally, recent research has revealed that the combination may target different areas in the retina to support total retinal health, photoreceptor health, and color vision.* • Made with hypoallergenic, vegan ingredients

Macular Support Formula is a combination high in antioxidants and botanicals designed to protect and support the macula, the central area of the retina responsible for sharp vision. Since the macula is extremely susceptible to free radical damage, the research emphasizes the importance of antioxidant supplementation in maintaining and improving macular health. N-acetyl-l-cysteine, a glutathione precursor, has been shown to protect against oxidative damage to the lens and to support healthy glutathione levels. Glutathione is one of the natural antioxidants found in retinal tissues. Bilberry, containing anthocyanidins, may help moderate visual fatigue and improve light to dark adjustments. Combined with these cofactors, grape seed extract helps provide antioxidant balance in the retina. This formula is also enhanced with lutein and zeaxanthin, the only two carotenoids found in macular pigment. Lutein and zeaxanthin promote the integrity and density of the macular pigment, as well as helps maintain the health of the optical lens. The antioxidant activity of carotenoids and vitamin C provide optimal macular protection and ocular health.* Made with hypoallergenic ingredients

Macular Support Formula is a combination high in antioxidants and botanicals designed to protect and support the macula, the central area of the retina responsible for sharp vision. Since the macula is extremely susceptible to free radical damage, the research emphasizes the importance of antioxidant supplementation in maintaining and improving macular health. N-acetyl-l-cysteine, a glutathione precursor, has been shown to protect against oxidative damage to the lens and to support healthy glutathione levels. Glutathione is one of the natural antioxidants found in retinal tissues. Bilberry, containing anthocyanidins, may help moderate visual fatigue and improve light to dark adjustments. Combined with these cofactors, grape seed extract helps provide antioxidant balance in the retina. This formula is also enhanced with lutein and zeaxanthin, the only two carotenoids found in macular pigment. Lutein and zeaxanthin promote the integrity and density of the macular pigment, as well as helps maintain the health of the optical lens. The antioxidant activity of carotenoids and vitamin C provide optimal macular protection and ocular health.* • Made with hypoallergenic ingredients

Numerous studies have reported statistically significant benefits of calcium supplementation for bone health. Magnesium, like calcium, is an essential bone matrix mineral that promotes healthy bone. A trial involving 2,038 older individuals indicated that higher intakes of magnesium were positively associated with bone mineralization for certain individuals.* • Made with hypoallergenic, vegan ingredients

Magnesium activates the enzymes necessary for a number of physiological functions, including neuromuscular contractions, cardiac function, and the regulation of the acid-alkaline balance in the body. In a cross-sectional study involving 210 elderly individuals, optimal magnesium intake was associated with positive mood, lipid metabolism, and lean body mass. Magnesium is necessary for the metabolism of carbohydrates, amino acids and fats, as well as energy production and the utilization of calcium, phosphorus, sodium, and potassium. In a 15-year study involving almost 5,000 young adults, higher intakes of magnesium were associated with healthy cardiovascular function and glucose utilization. Another large cross-sectional study found that magnesium intake was positively associated with bone mineral density in certain subgroups. This vital mineral also helps utilize some vitamins, including vitamin B6, vitamin C, and vitamin E. Magnesium (glycinate) is less likely to cause loose stools than other forms of magnesium.* • Made with hypoallergenic, vegan ingredients

Magnesium activates the enzymes necessary for a number of physiological functions, including neuromuscular contractions, cardiac function, and the regulation of the acid-alkaline balance in the body. In a cross-sectional study involving 210 elderly individuals, optimal magnesium intake was associated with positive mood, lipid metabolism, and lean body mass. Magnesium is necessary for the metabolism of carbohydrates, amino acids and fats, as well as energy production and the utilization of calcium, phosphorus, sodium, and potassium. In a 15-year study involving almost 5,000 young adults, higher intakes of magnesium were associated with healthy cardiovascular function and glucose utilization. Another large cross-sectional study found that magnesium intake was positively associated with bone mineral density in certain subgroups. This vital mineral also helps utilize some vitamins, including vitamin B6, vitamin C, and vitamin E. Magnesium (glycinate) is less likely to cause loose stools than other forms of magnesium.* • Made with hypoallergenic, vegan ingredients

Magnesium activates the enzymes necessary for a number of physiological functions, including neuromuscular contractions, cardiac function, and the regulation of the acid-alkaline balance in the body. In a cross-sectional study involving 210 elderly individuals, optimal magnesium intake was associated with positive mood, lipid metabolism, and lean body mass. Magnesium is necessary for the metabolism of carbohydrates, amino acids and fats, as well as energy production and the utilization of calcium, phosphorus, sodium, and potassium. In a 15-year study involving almost 5,000 young adults, higher intakes of magnesium were associated with healthy cardiovascular function and glucose utilization. Another large cross-sectional study found that magnesium intake was positively associated with bone mineral density in certain subgroups. This vital mineral also helps utilize some vitamins, including vitamin B6, vitamin C, and vitamin E. Magnesium (glycinate) is less likely to cause loose stools than other forms of magnesium.* • Made with hypoallergenic, vegan ingredients

Magnesium activates the enzymes necessary for a number of physiological functions, including neuromuscular contractions, cardiac function, and the regulation of the acid-alkaline balance in the body. In a cross-sectional study involving 210 elderly individuals, optimal magnesium intake was associated with positive mood, lipid metabolism, and lean body mass. Magnesium is necessary for the metabolism of carbohydrates, amino acids and fats, as well as energy production and the utilization of calcium, phosphorus, sodium, and potassium. In a 15-year study involving almost 5,000 young adults, higher intakes of magnesium were associated with healthy cardiovascular function and glucose utilization. Another large cross-sectional study found that magnesium intake was positively associated with bone mineral density in certain subgroups. This vital mineral also helps utilize some vitamins, including vitamin B6, vitamin C, and vitamin E. Magnesium (glycinate) is less likely to cause loose stools than other forms of magnesium.*

Magnesium EasySticks Features • Great-tasting fruit flavored powder • Sprinkle directly in the mouth with no water or mixing needed • Offers bioavailable chelated magnesium malate and potassium citrate* • Enhanced with blueberry fruit powder; consumption of blueberries has been associated with cardiovascular and brain health*

Melatonin is primarily associated with supporting the body’s natural sleep cycle and promoting normal immune function. It also scavenges free radicals. Randomized studies have revealed the potential for melatonin to positively support colon, breast, prostate, and lung tissues. This function in the lungs helps tamp down an over-reactive immune system triggered by COVID-19 or other viral illnesses.

Melatonin is primarily associated with supporting the body’s natural sleep cycle and promoting normal immune function. It also scavenges free radicals. Randomized studies have revealed the potential for melatonin to positively support colon, breast, prostate, and lung tissues. This function in the lungs helps tamp down an over-reactive immune system triggered by COVID-19 or other viral illnesses.

CoQ10 is a component of the mitochondria and plays a key role in the synthesis of ATP. Ubiquinol is the activated form of CoQ10. B vitamins are important cofactors needed to fuel the Krebs cycle, while optimal serum levels of magnesium are associated with healthy mitochondrial metabolism and nutrient transport. Acetyl-l-carnitine provides carnitine to transport long-chain fatty acids into the mitochondria for energy as well as an acetyl group for the synthesis of the Krebs cycle precursor acetyl-CoA. Highly pure creatine monohydrate helps enhance the production of the ATP by acting as a precursor. This formula provides antioxidant support from vitamins C and E, as well as additional antioxidant support from grape seed extract, resveratrol, alpha lipoic acid, and n-acetyl-l-cysteine. These nutrients and bioactive neutralize the free radicals generated during energy production in the mitochondria. In a double-blind, placebo-controlled crossover study, the combination of creatine, CoQ10, and alpha lipoic acid supported energy production and antioxidant status within the mitochondria.* Mitochondria-ATP provides nutrients and antioxidants to support ATP production, which promotes energy generation and mitochondrial metabolic health for the efficient transport of energy within cells.*

Pure Encapsulations' MSM (methylsulfonylmethane or dimethylsulfone) is a source of organic sulfur found naturally in the human body. MSM, the major metabolite of DMSO (dimethyl sulfoxide), is 34% elemental sulfur, a compound that is crucial in maintaining healthy tissues. While sulfur supports many functions, it is well known for maintaining connective tissue health. Sulfur also supports tissue containing significant amounts of collagen and keratin, including hair, skin, and nails. Sulfur is essential in methionine, cysteine and serum protein metabolism. Preliminary evidence suggests that MSM may also provide potential support for healthy immune and respiratory function.*

Pure Encapsulations' MSM (methylsulfonylmethane or dimethylsulfone) is a source of organic sulfur found naturally in the human body. MSM, the major metabolite of DMSO (dimethyl sulfoxide), is 34% elemental sulfur, a compound that is crucial in maintaining healthy tissues. While sulfur supports many functions, it is well known for maintaining connective tissue health. Sulfur also supports tissue containing significant amounts of collagen and keratin, including hair, skin, and nails. Sulfur is essential in methionine, cysteine and serum protein metabolism. Preliminary evidence suggests that MSM may also provide potential support for healthy immune and respiratory function.*

N-Acetyl-l-Cysteine (NAC) is a derivative of the dietary amino acid l-cysteine. NAC has a high affinity for lung tissue, which it supports through mucolytic and antioxidant action. NAC supports tissue levels of glutathione, a key component of the antioxidant defense system.*

N-Acetyl-l-Cysteine (NAC) is a derivative of the dietary amino acid l-cysteine. NAC has a high affinity for lung tissue, which it supports through mucolytic and antioxidant action. NAC supports tissue levels of glutathione, a key component of the antioxidant defense system.* • Supports cellular antioxidant defense system* • Promotes healthy lung tissue* • Made with hypoallergenic ingredients

Niacitol® contains inositol nicotinate, a form of no-flush niacin (vitamin B3)that has been used in Europe for over thirty years for healthy cardiovascular support. Niacitol® is a well-tolerated form of vitamin B3 and is unlikely to cause the flushing or other side effects that are associated with niacin. Inositol nicotinate is composed of one molecule of inositol and six molecules of niacin.* • Helps breakdown and utilize fats, proteins, and carbohydrates* • May promote the formation of digestive tissues* • Made with hypoallergenic, vegan ingredients

A gentle formula that is well tolerated by sensitive individuals, this multivitamin/mineral formula is packed with nutrients and minerals to support a healthy lifestyle. Nutrient 950 is a complete hypoallergenic multi-vitamin and multi-mineral supplement. Our multivitamin is complete with activated vitamins and chelated minerals to promote optimal absorption.*

A gentle formula that is well tolerated by sensitive individuals, this multivitamin/mineral formula is packed with nutrients and minerals to support a healthy lifestyle. Nutrient 950 is a complete hypoallergenic multi-vitamin and multi-mineral supplement. Our multivitamin is complete with activated vitamins and chelated minerals to promote optimal absorption.*

A gentle formula that is well tolerated by sensitive individuals, this multivitamin/mineral formula is packed with nutrients and minerals to support a healthy lifestyle. Nutrient 950 without Iron is a hypoallergenic multivitamin and mineral dietary supplement formulated to provide optimal nutritional support. Nutrient 950 without Iron offers an advanced mineral delivery system to promote proper absorption of nutrients.*

A gentle formula that is well tolerated by sensitive individuals, this multivitamin/mineral formula is packed with nutrients and minerals to support a healthy lifestyle. Nutrient 950 without Iron is a hypoallergenic multivitamin and mineral dietary supplement formulated to provide optimal nutritional support. Nutrient 950 without Iron offers an advanced mineral delivery system to promote proper absorption of nutrients.*

The Mediterranean olive tree, Olea europaea, defends itself against bacteria, fungi, parasites, and insects through eutrophic compounds it produces. Its leaf extract is popular in herbal and folk remedies and has benefited individuals for 150 years. The active nutrient in the olive leaf is oleuropein, a phenolic glucoside (structurally classified as an iridoid). The olive leaf also contains the bioflavonoids rutin, luteolin, and hesperidin, which work synergistically with oleuropein to enhance its natural activity. Olive Leaf extract provides natural protection and a healthy environment for cells, without suppressing immune system function or harming beneficial microflora.* • Made with hypoallergenic, vegan ingredients

For men and women age 18 and over Special Features: • Convenient one-capsule-per-day dosing • The antioxidant complex includes alpha lipoic acid and a blend of CoQ10 and sustained release water-soluble nanosized MicroActive® Q10 • Choline and inositol for healthy cognitive function* • Supports cellular health with 500 mcg lycopene and 50 mcg (2,000 IU) vitamin D* • Helps maintain macular and retinal health with 3 mg lutein and 500 mcg zeaxanthin* • Once-daily multivitamin with sustained-release CoQ10 • Provides vitamins A, B, C, D and E in highly bioavailable forms* • Made with hypoallergenic, vegetarian ingredients

Includes Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF), the naturally occurring, universally metabolized form of folate. Convenient one-capsule-per-day dosing. The antioxidant complex includes alpha lipoic acid and a blend of CoQ10 and sustained release water-soluble nanosized MicroActive® Q10, and choline and inositol for healthy cognitive function.* Supports cellular health with 500 mcg lycopene and 50 mcg (2,000 IU) vitamin D. Helps maintain macular and retinal health with 3 mg lutein and 500 mcg zeaxanthin.*

1,000 mg supercritical CO2 extracted, triglyceride-form EPA and DHA in a convenient, once-daily dose O.N.E.™ Omega offers 1,000 mg of EPA/DHA in each soft-gel, twice the potency of other fish oils, providing powerful omega-3 fatty acid support for cardiovascular, joint, cognitive and skin health. Each soft-gel contains fish oil produced through a unique solvent-free, supercritical CO2-based extraction method. This method utilizes a low-temperature, oxygen-free process to prevent oxidation reactions, resulting in pure, concentrated fish oil.*

Pyridoxal 5' phosphate (P5P) is the active metabolite of pyridoxine and is the predominant form of plasma B6. P5P is required for proper absorption of B12 and magnesium, and for the production of gastric HCl. It is an important coenzyme in the metabolism of carbohydrates, fats, and proteins, and the elongation of essential fatty acids. It is required for the production of antibodies and red blood cells. P5P facilitates the release of glycogen (used in energy production) from the liver and muscles. In addition, P5P helps maintain the balance of sodium and potassium, which regulates body fluids and promotes the healthy functioning of the nervous and musculoskeletal systems.* • The main form of plasma B6* • Helps metabolize carbohydrates, fats and proteins* • Made with hypoallergenic, vegan ingredients

Pyridoxal 5' phosphate (P5P) is the active metabolite of pyridoxine and is the predominant form of plasma B6. P5P is required for proper absorption of B12 and magnesium, and for the production of gastric HCl. It is an important coenzyme in the metabolism of carbohydrates, fats, and proteins, and the elongation of essential fatty acids. It is required for the production of antibodies and red blood cells. P5P facilitates the release of glycogen (used in energy production) from the liver and muscles. In addition, P5P helps maintain the balance of sodium and potassium, which regulates body fluids and promotes the healthy functioning of the nervous and musculoskeletal systems.* • The main form of plasma B6* • Helps metabolize carbohydrates, fats and proteins* • Made with hypoallergenic, vegan ingredients

Pantethine is the active form of the B vitamin pantothenic acid and is a major component of coenzyme A, or CoA. In cells, CoA is essential for fatty acid transport and fatty acid metabolism. Several human studies demonstrate the ability of pantethine to maintain healthy utilization and metabolism of various lipids, promoting healthy cardiovascular function.* • Made with hypoallergenic, vegan ingredients

Pantethine is the active form of the B vitamin pantothenic acid and is a major component of coenzyme A, or CoA. In cells, CoA is essential for fatty acid transport and fatty acid metabolism. Several human studies demonstrate the ability of pantethine to maintain healthy utilization and metabolism of various lipids, promoting healthy cardiovascular function.* • Made with hypoallergenic, vegan ingredients

This vegetarian formula provides wide range herbal and nutritional support for the adrenal glands. Panax ginseng and Eleutherococcus senticosus, or eleuthero, are highly recognized adaptogens, promoting physiological balance and moderating occasional stress. In part, they help to moderate the production of adrenocorticotrophic hormone (ACTH) and ultimately corticosterone activity. Corticosterone promotes the conversion of amino acids into carbohydrates and glycogen by the liver and stimulates glycogen formation in the tissues, supporting optimal energy reserves. Rhodiola rosea, containing rosavins and salidrosides, also acts to balance hypothalamic-pituitary-adrenal activity. Rhodiola can have a calming effect on the central nervous system and supports healthy thyroid, thymus, and adrenal gland function. In particular, rhodiola may moderate the effects of occasional physical and emotional stress. Recently, a double-blind cross-over study suggests that rhodiola may help to moderate mild fatigue under stressful conditions. Astragalus and ashwagandha promote immune function and complement the adaptogenic activity of this formula. Calcium pantothenate, a vitamin B5 derivative, is essential for activating the adrenals. Collectively, these ingredients support the health and activity of the adrenal glands.*

This vegetarian formula provides wide range herbal and nutritional support for the adrenal glands. Panax ginseng and Eleutherococcus senticosus, or eleuthero, are highly recognized adaptogens, promoting physiological balance and moderating occasional stress. In part, they help to moderate the production of adrenocorticotrophic hormone (ACTH) and ultimately corticosterone activity. Corticosterone promotes the conversion of amino acids into carbohydrates and glycogen by the liver and stimulates glycogen formation in the tissues, supporting optimal energy reserves. Rhodiola rosea, containing rosavins and salidrosides, also acts to balance hypothalamic-pituitary-adrenal activity. Rhodiola can have a calming effect on the central nervous system and supports healthy thyroid, thymus, and adrenal gland function. In particular, rhodiola may moderate the effects of occasional physical and emotional stress. Recently, a double-blind cross-over study suggests that rhodiola may help to moderate mild fatigue under stressful conditions. Astragalus and ashwagandha promote immune function and complement the adaptogenic activity of this formula. Calcium pantothenate, a vitamin B5 derivative, is essential for activating the adrenals. Collectively, these ingredients support the health and activity of the adrenal glands.*

• Enhanced antioxidant support* • Wide range support for cellular, macular, cognitive, skin, heart, nerve, and liver health* Vitamin/Mineral Distinctions: • With choline and inositol for comprehensive B-complex support* Special Features: • Cell Health Polyphenols* Includes polyphenols from blueberry, grape seed, olive fruit, pomegranate, green tea and quercetin for optimal cell health. Alpha lipoic acid and n-acetyl-l-cysteine act as complementary cofactors for added antioxidant protection.* • MacularSynergy Complex* Supports the integrity of the macula and retina with lutein and zeaxanthin. Synergistic cofactors include vitamin C, vitamin E, zinc and carotenoids.* Polyphenol Nutrients is a multivitamin and mineral formula for overall health and cellular protection.

• Enhanced antioxidant support* • Wide range support for cellular, macular, cognitive, skin, heart, nerve, and liver health* Vitamin/Mineral Distinctions: • With choline and inositol for comprehensive B-complex support* Special Features: • Cell Health Polyphenols* Includes polyphenols from blueberry, grape seed, olive fruit, pomegranate, green tea and quercetin for optimal cell health. Alpha lipoic acid and n-acetyl-l-cysteine act as complementary cofactors for added antioxidant protection.* • MacularSynergy Complex* Supports the integrity of the macula and retina with lutein and zeaxanthin. Synergistic cofactors include vitamin C, vitamin E, zinc and carotenoids.* Polyphenol Nutrients is a multivitamin and mineral formula for overall health and cellular protection.

Potassium and magnesium are both essential for healthy nerve impulse function, muscle contraction, cardiovascular function, acid/alkaline balance, and carbohydrate and nutrient metabolism. Magnesium also plays an important role in facilitating potassium utilization, helping to provide optimal support.

Essential to cardiovascular function *Potassium activates many enzymatic reactions and is essential to a number of physiologic processes, including: transmission of nerve impulses; contraction of cardiac, smooth, and skeletal muscles; gastric secretion; renal function; tissue synthesis; and carbohydrate metabolism. Potassium is the major cation of intracellular fluid and is essential for maintenance of acid-alkaline balance, isotonicity, and electrodynamic characteristics of the cell. In addition, it regulates blood pressure and works with sodium to regulate water balance, heart rhythm, and normal nerve and muscle function.

Potassium activates many enzymatic reactions and is essential to a number of physiologic processes, including transmission of nerve impulses, muscle contraction, gastric secretions, renal function, tissue synthesis, and carbohydrate metabolism. Potassium is the major cation of intracellular fluid and is essential for maintenance of acid-alkaline balance, isotonicity, and electrodynamic characteristics of the cell. In addition, it works with sodium to maintain healthy water balance, heart rhythm, and nerve and muscle function. Research suggests that adequate potassium intake may support healthy blood flow and cardiovascular health.*

Pregnenolone, 3-beta-hydroxy-5-pregnen-20-one, is a natural steroid hormone produced in the body from cholesterol. It has been described as the “Grandmother of all Steroid Hormones,” since all steroid hormones, over 150 of them, are derived from pregnenolone. Pregnenolone has been linked with positive support of the immune system, mood and memory. In the body, it is converted to DHEA and/or progesterone. It is likely that the body will convert pregnenolone appropriately, according to its needs. Studies show that the body makes 60% less of this hormone at age 75 than it does at age 35.*

Now enhanced with: • 1 mg of folate from 40% folic acid and 60% Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF), the naturally occurring, universally metabolized form of folate • Increased vitamin D based on revised RDA requirements for pregnancy • Vitamin K to support healthy carboxylation of proteins for blood clotting and bone* • 100 mg of choline to support fetal central nervous system development* Vitamin Distinctions: • 1 mg of folate from 40% folic acid and 60% L-5-MTHF for optimal neural and cellular development* • 27 mg of iron and 150 mcg of iodine to meet enhanced requirements during pregnancy* • 100 mg of choline to support hormone, neurotransmitter, DNA, protein and energy production*

This item has been discontinued by the manufacturer

Each lozenge provides 1,000 mcg of methylcobalamin (the active form of vitamin B12) and 400 mcg of Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF), the naturally occurring, universally metabolized form of folate. Optimal levels of these B vitamins have been associated with cellular, cardiovascular, neurological and psychological health. Activated B vitamins provide methyl groups to support healthy methylation, a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, hormone and neurotransmitter production, and energy metabolism. This great-tasting, fruit-flavored lozenge contains no sugar, magnesium stearate, or artificial colors or flavors.*

Proper nutrition is essential for overall health‚ and is especially important for growing bodies. Children need a variety of vitamins‚ minerals‚ and other nutrients to make sure that they are able to stay healthy and active. Unfortunately‚ it can be difficult to ensure that picky eaters consume a balanced diet. Rest easier with a convenient supplement like Pure Encapsulations' PurePals with Iron. In addition‚ each chewable tablet provides citrus bioflavonoids and choline. Choline is a water-soluble nutrient that allows cells to communicate with each other. Bioflavonoids have antioxidant properties and are responsible for the bright colors of fruits. Citrus bioflavonoids include quercetin and rutin‚ and may help alleviate inflammation while supporting veins. These chewable tablets have a natural cherry flavor; what they don't have is any added sugar‚ fructose‚ or artificial flavors or sweeteners. Xylitol is a natural sweetener that promotes middle ear and dental health.

“Pycnogenol” originally denoted all proanthocyanidin extracts, regardless of source. However, it now refers specifically to maritime pine bark. The mixture of proanthocyanidins in pine bark supports vascular endothelial integrity by stabilizing collagenous membranes. It also promotes vascular function by modulating nitric oxide levels. In addition to facilitating vitamin C regeneration and preserving vitamin E, Pycnogenol® is a hydroxyl and superoxide radical scavenger. Collectively, these actions promote the health of blood vessels.* The term “pycnogenol” originally denoted the generic proanthocyanidin extracts. However, it is now a registered trademark name referring specifically to the maritime pine extract. Pycnogenol® contains a minimum of 85% pycnogenols by weight. The maritime pine was the original source of proanthocyanidins studied and researched by Jacques Masquelier, Ph.D.

You’re exposed to free radicals every day‚ no matter where you live. There are natural sources of free radicals in the air that we breathe‚ but free radicals are also commonly derived from things like tobacco‚ heavy metals (such as mercury)‚ and pesticides. Free radicals are extremely reactive molecules that can cause disruption in bodily processes like the production of DNA‚ RNA‚ and fats. If this happens‚ your body can experience poor cell functioning and lowered immunity. One way to combat the effects of free radicals is to maintain a healthy‚ organic diet that is rich in antioxidants. Antioxidants neutralize free radicals‚ which can prevent or even reverse their potential damage. It’s understandable that in today’s busy world‚ that you may not have time to eat a proper diet. Alternatively‚ you may have limited access (or no access) to organic‚ pesticide-free foods. This is where a supplement like Pure Encapsulations’ Quercetin comes in. Quercetin also works to protect your arteries from harmful plaque buildup. Other possible benefits include: Support for healthy blood pressure levels, reduction of symptoms of bladder pain and the urge to urinate excessively‚ if you have a urinary tract infection, reduction of prostate inflammation*

SAMe (S-adenosylmethionine) is a metabolite present in all living cells. It functions as a donor of methyl groups in over 100 different reactions and contributes to the synthesis, activation and/or metabolism of hormones, neurotransmitters, nucleic acids, phospholipids and proteins. Methyl groups act as a signal throughout the body, regulating genetic expression and cellular function. SAMe also functions as a precursor molecule for glutathione and promotes polyamine synthesis to promote healthy cellular function. Clinical trials indicate that SAMe administration enhances glutathione production in hepatic tissue and red blood cells. SAMe also targets cognitive function and positive mood, as indicated in over 40 clinical studies. In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood believed to be due to its support for neurotransmitter monoamine synthesis and function, including dopamine and serotonin. It also promotes healthy protein turnover and maintains healthy phospholipid methylation to support phosphatidylcholine production and cellular membrane integrity and fluidity. Studies suggest it may enhance joint comfort and flexibility as well. In a meta-analysis involving 11 studies, SAMe offered statistically significant support for joint function. It is believed to enhance joint comfort and function by supporting proteoglycan synthesis, as well as helping to stabilize and protect the proteoglycans.*

Throughout the world‚ an herb called saw palmetto has been used by men to support their overall well-being. Specifically‚ it works to support the prostate, the gland that produces semen‚ and surrounds the tube that carries urine out of the bladder in order to eliminate liquid waste. Saw Palmetto 320 by Pure Encapsulations promotes the healthy metabolism of testosterone‚ which is the primary male sex hormone. Testosterone levels may decline with age; therefore‚ a lack of testosterone may be related to the increased chance that older males have of developing an enlarged prostate. In addition‚ the saw palmetto extract in Saw Palmetto 320 works to support the urinary tract. This is because it may alleviate symptoms associated with prostate gland enlargement (aka benign prostatic hyperplasia, or BPH). While it typically isn't a sign of more serious health problems‚ an enlarged prostate can put increased pressure on the urethra; as a result‚ you may feel the need to urinate more frequently--having to wake up and go to the bathroom at night is common. Another common--and sometimes embarrassing--indication of BPH--is dribbling after urination. Every softgel of Saw Palmetto 320 contains 320 milligrams of Serenoa repens (saw palmetto) fruit extract. This extract has been standardized to ensure that it provides sufficient levels of active compounds: 0.15 percent phytosterols and 85 percent total fatty acids. Phytosterols are plant sterols that may support cardiovascular health by latching onto cholesterol receptors in the intestines.*

Throughout the world‚ an herb called saw palmetto has been used by men to support their overall well-being. Specifically‚ it works to support the prostate, the gland that produces semen‚ and surrounds the tube that carries urine out of the bladder in order to eliminate liquid waste. Saw Palmetto 320 by Pure Encapsulations promotes the healthy metabolism of testosterone‚ which is the primary male sex hormone. Testosterone levels may decline with age; therefore‚ a lack of testosterone may be related to the increased chance that older males have of developing an enlarged prostate. In addition‚ the saw palmetto extract in Saw Palmetto 320 works to support the urinary tract. This is because it may alleviate symptoms associated with prostate gland enlargement (aka benign prostatic hyperplasia, or BPH). While it typically isn't a sign of more serious health problems‚ an enlarged prostate can put increased pressure on the urethra; as a result‚ you may feel the need to urinate more frequently--having to wake up and go to the bathroom at night is common. Another common--and sometimes embarrassing--indication of BPH--is dribbling after urination. Every softgel of Saw Palmetto 320 contains 320 milligrams of Serenoa repens (saw palmetto) fruit extract. This extract has been standardized to ensure that it provides sufficient levels of active compounds: 0.15 percent phytosterols and 85 percent total fatty acids. Phytosterols are plant sterols that may support cardiovascular health by latching onto cholesterol receptors in the intestines.*

Saw palmetto has been used safely for decades to support proper prostate and urinary function. Its primary mode of action involves maintaining healthy testosterone metabolism. In a recently published JAMA meta-analysis involving 18 randomized controlled trials and almost 3,000 men, saw palmetto promoted healthy urinary flow. Pygeum africanum may maintain healthy prostaglandin and prolactin metabolism in the prostate. Pumpkin seed oil provides essential fatty acids and zinc, important for prostate health. Nettle root, also known as stinging nettles or Urtica dioica, has indicated the ability to support healthy enzyme activity and maintain healthy hormone metabolism in prostate cells. In a multicenter study examining the effect of nettle root extract in over 5,000 individuals, the extract supported prostate health in the majority of subjects.* • Supports prostate health* • Helps maintain healthy prostate function* • Made with hypoallergenic ingredients

Saw palmetto has been used safely for decades to support proper prostate and urinary function. Its primary mode of action involves maintaining healthy testosterone metabolism. In a recently published JAMA meta-analysis involving 18 randomized controlled trials and almost 3,000 men, saw palmetto promoted healthy urinary flow. Pygeum africanum may maintain healthy prostaglandin and prolactin metabolism in the prostate. Pumpkin seed oil provides essential fatty acids and zinc, important for prostate health. Nettle root, also known as stinging nettles or Urtica dioica, has indicated the ability to support healthy enzyme activity and maintain healthy hormone metabolism in prostate cells. In a multicenter study examining the effect of nettle root extract in over 5,000 individuals, the extract supported prostate health in the majority of subjects.* • Supports prostate health* • Helps maintain healthy prostate function* • Made with hypoallergenic ingredients

Saw palmetto has been used safely for decades to support proper prostate and urinary function. Its primary mode of action involves maintaining healthy testosterone metabolism. In a recently published JAMA meta-analysis involving 18 randomized controlled trials and almost 3,000 men, saw palmetto promoted healthy urinary flow. Pygeum africanum may maintain healthy prostaglandin and prolactin metabolism in the prostate. Pumpkin seed oil provides essential fatty acids and zinc, important for prostate health. Nettle root, also known as stinging nettles or Urtica dioica, has indicated the ability to support healthy enzyme activity and maintain healthy hormone metabolism in prostate cells. In a multicenter study examining the effect of nettle root extract in over 5,000 individuals, the extract supported prostate health in the majority of subjects.* • Supports prostate health* • Helps maintain healthy prostate function* • Made with hypoallergenic ingredients

Silymarin is a milk thistle extract that nutritionally supports liver function. This highly active botanical protects the liver from free radical damage, supports glutathione concentrations and promotes superoxide dismutase activity. Milk thistle extract also stimulates protein synthesis in hepatic cells* • Supports liver function* • Possesses antioxidant activity* • Made with hypoallergenic, vegan ingredients

The trace mineral strontium supports healthy osteoblast differentiation, osteoblast collagen formation and balanced osteoclast activity, maintaining bone tensile strength. In two separate clinical trials involving a total of more than 2,000 women, strontium supplementation supported healthy vertebrae integrity and composition. In a preliminary analysis of a three-year placebo-controlled, double-blind study of 5,091 postmenopausal women, strontium supplementation promoted healthy hip bones. Since strontium is absorbed using calcium transport mechanisms, strontium supplements should not be taken at the same time as calcium supplements or calcium containing foods. While supplementing with strontium, adequate calcium intake should be maintained.*

The trace mineral strontium supports healthy osteoblast differentiation, osteoblast collagen formation and balanced osteoclast activity, maintaining bone tensile strength. In two separate clinical trials involving a total of more than 2,000 women, strontium supplementation supported healthy vertebrae integrity and composition. In a preliminary analysis of a three-year placebo-controlled, double-blind study of 5,091 postmenopausal women, strontium supplementation promoted healthy hip bones. Since strontium is absorbed using calcium transport mechanisms, strontium supplements should not be taken at the same time as calcium supplements or calcium containing foods. While supplementing with strontium, adequate calcium intake should be maintained.*

Systemic Enzyme Complex is formulated to support the overall health of the musculoskeletal system by maintaining healthy cell function as well as joint and cartilage health.* 30 mg pure pancreatin (porcine) (lactose-free) (50,000 USP units protease) 176 mg protease 6.0 (60,000 HUT) 120 mg Serrazimes® (protease blend) (10,000 U) 17 mg bromelain (2,400 gdu/g) 120 mg papain (800 TGU/mg) 120 mg rutin 100 mg trypsin (porcine) (1:150) (11,250 USP units) 75 mg chymotrypsin (porcine) (2,550 USP units) 3 mg boswellia serrata extract (gum resin) (standardized to contain 70% boswellic acids) (175 mg)

Taurine is the most abundant free amino acid in the brain, heart, and nervous system, and it plays a role in the healthy functioning of the brain, heart, gallbladder, eyes, and vascular system. It facilitates the passage of sodium, potassium, and, possibly, calcium and magnesium ions into and out of cells, and electrically stabilizes cell membranes. It maintains healthy cAMP activity, which activates important enzymes in the heart muscle, and contributes to the muscle’s contractibility. Taurine is an important component of bile acids which aid in the absorption of fat-soluble vitamins. It aids the body’s chemistry to support the normal detoxification process. Dietary taurine promotes the formation of taurocholate, a substance which increases cholesterol secretion in the bile and also supports fat metabolism in the liver.* • Made with hypoallergenic, vegan ingredients

The PureResponse™ formula Th2 Modulator is designed to support healthy Th1/Th2 balance and mucosal health. Modulating Th2 status helps to maintain Th1/Th2 balance and offers support for self-tissue response. Th2 response is affected by stress, aging, and cytokine changes resulting from metabolic, hormonal, physiological, and environmental factors. The product helps support healthy modulation of Th2 cytokines, and eosinophil and mast cell activity. It also helps maintain healthy modulation of mucosal immune responses to environmental factors. Th2 modulation may be indicated when addressing immune balance in the sinus, respiratory, urinary, and intestinal tracts. Perilla maintains healthy upper respiratory cytokine levels in animal models of Th2 dominance. It also supports cytokine homeostasis of GI mucosal tissue. In a randomized controlled trial involving 50 individuals, 150 mg of Perilla frutescens extract twice daily offered statistically significant support for GI comfort. N-acetyl-l-cysteine (NAC) offers mucolytic properties and promotes tissue levels of glutathione – a key component of the antioxidant defense system – to support the body's natural defense system. Lymphocytes rely on glutathione to function properly. It is believed to be through this antioxidant mechanism that NAC supports healthy Th1/Th2 balance and cytokine production to maintain tissue health. A multicenter, randomized, double-blind trial with 262 participants indicated that NAC supplementation for six months supported upper respiratory tract and immune system health. Quercetin is known for its antioxidant activity and immune support properties, including support for Th1/Th2 balance and cytokine balance. Astragalus may help modulate the relationship between Th1 and Th2 cytokines.* • Part of the PureResponse™ Immune Protocol* for healthy immune balance and function* • Contains a blend of N-acetyl-l-cysteine (NAC), quercetin, perilla seed and astragalus extracts • Offers support for self-tissue response*

• 3,750 mcg (12,500 IU) natural beta carotene with mixed carotenoids for advanced antioxidant protection* • ChromeMate® chromium polynicotinate to promote optimal glucose utilization* • Without iron • CardioHealth Complex* • LiverEnhance Blend* • Supports cardiovascular and liver health* • Comprehensive vitamin and mineral formula • Made with hypoallergenic, vegetarian ingredients

• 3,750 mcg (12,500 IU) natural beta carotene with mixed carotenoids for advanced antioxidant protection* • ChromeMate® chromium polynicotinate to promote optimal glucose utilization* • Without iron • CardioHealth Complex* • LiverEnhance Blend* • Supports cardiovascular and liver health* • Comprehensive vitamin and mineral formula • Made with hypoallergenic, vegetarian ingredients

UltraMag Magnesium utilizes an innovative microencapsulation technology to enhance the absorption of magnesium. This technology creates a phospholipid bilayer around the mineral that is similar to a liposome, increasing solubility in the gastrointestinal fluids and facilitating absorption across membranes. In a comparative crossover study, magnesium in the Sucrosomial® matrix was compared to other forms of magnesium in human subjects. Twenty-four-hour blood and urinary magnesium measurements indicated superior absorption of Sucrosomial® magnesium compared to magnesium citrate, glycinate, and oxide.* • Exclusive first to market among professional brands • Phospholipid bilayer microencapsulation technology protects mineral in gastrointestinal lumen, increases dissolvability, and easily crosses membranes • Clinically studied • Promotes muscle relaxation, bone and cardiovascular health*

Vitamin D promotes intestinal calcium and phosphorous absorption, and reduces urinary calcium loss, essential mechanisms for maintaining proper calcium levels in the body and healthy bone composition. Research indicates that it also supports immune cell activity, maintains healthy cell metabolism, and promotes cellular health—including support for breast and prostate tissue, in part by helping to maintain healthy angiogenesis balance. A role for vitamin D in supporting colon health by promoting healthy cellular function has also been suggested. Vitamin D's role in immune health has long been established; vitamin D receptors are found on a number of immune cells, including lymphocytes and macrophages, supporting healthy immune cell activation. Vitamin D also supports cardiovascular function in some individuals.* • Supports healthy bone composition* • Promotes cellular support for breast and prostate tissue* • Made with hypoallergenic, vegetarian ingredients

Vitamin D promotes intestinal calcium and phosphorous absorption, and reduces urinary calcium loss, essential mechanisms for maintaining proper calcium levels in the body and healthy bone composition. Research indicates that it also supports immune cell activity, maintains healthy cell metabolism, and promotes cellular health—including support for breast and prostate tissue, in part by helping to maintain healthy angiogenesis balance. A role for vitamin D in supporting colon health by promoting healthy cellular function has also been suggested. Vitamin D's role in immune health has long been established; vitamin D receptors are found on a number of immune cells, including lymphocytes and macrophages, supporting healthy immune cell activation. Vitamin D also supports cardiovascular function in some individuals.* • Supports healthy bone composition* • Promotes cellular support for breast and prostate tissue* • Made with hypoallergenic, vegetarian ingredients

Vitamin D promotes intestinal calcium and phosphorous absorption, and reduces urinary calcium loss, essential mechanisms for maintaining proper calcium levels in the body and healthy bone composition. Research indicates that it also supports immune cell activity, maintains healthy cell metabolism, and promotes cellular health—including support for breast and prostate tissue, in part by helping to maintain healthy angiogenesis balance. A role for vitamin D in supporting colon health by promoting healthy cellular function has also been suggested. Vitamin D's role in immune health has long been established; vitamin D receptors are found on a number of immune cells, including lymphocytes and macrophages, supporting healthy immune cell activation. Vitamin D also supports cardiovascular function in some individuals.* • Supports healthy bone composition* • Promotes cellular support for breast and prostate tissue* • Made with hypoallergenic, vegetarian ingredients

Zinc plays an important role in supporting the body's natural defense system, as well as nutrient utilization. It is a constituent of over two dozen enzymes involved in digestion and metabolism, including carbonic anhydrase, which is vital to tissue respiration. Zinc is essential for the healthy storage and metabolism of carbohydrates, as well as the absorption and function of B vitamins. Zinc plays a fundamental role in collagen formation and healthy tissue development. This mineral contributes to healthy prostatic function, and is essential for normal fetal and reproductive development.* • Supports immune system function* • Supports reproductive health* • Made with hypoallergenic, vegen ingredients